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KH176 under development for rare mitochondrial disease: a first in man randomized controlled clinical trial in healthy male volunteers

BACKGROUND: Mitochondrial disorders are a clinically, biochemically and genetically heterogeneous group of multi-system diseases, with an unmet medical need for treatment. KH176 is an orally bio-available small molecule under development for the treatment of mitochondrial(−related) diseases. The com...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Koene, Saskia, Spaans, Edwin, Van Bortel, Luc, Van Lancker, Griet, Delafontaine, Brant, Badilini, Fabio, Beyrath, Julien, Smeitink, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644106/
https://ncbi.nlm.nih.gov/pubmed/29037240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-017-0715-0
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