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Rectal and sublingual administration of tacrolimus: a single-dose pharmacokinetic study in healthy volunteers

AIMS: The immunosuppressant tacrolimus is usually administered orally. When this is not feasible, other routes of administration may be useful. Previous research suggested that tacrolimus may be applied sublingually or rectally. Pharmacokinetic data are sparse. The aim of this study was to investiga...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Stifft, Frank, Vanmolkot, Floris, Scheffers, Ingrid, van Bortel, Luc, Neef, Cees, Christiaans, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243873/
https://ncbi.nlm.nih.gov/pubmed/24809233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12420
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