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Performance and consistency of a fluorescence-based high-throughput screening assay for use in Babesia drug screening in mice
In this study, we evaluated the validity of a fluorescence-based assay using SYBR Green I (SG I) stain for screening antibabesial compounds against B. microti in mice. Two different hematocrits (HCTs; 2.5% and 5%) were used. Correlating relative fluorescence units (RFUs) with parasitemia showed sign...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643553/ https://ncbi.nlm.nih.gov/pubmed/29038534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13052-5 |
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