Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas

Circulating tumor cells (CTCs) play a major role in the metastasis and recurrence of hepatocellular carcinoma (HCC). Here, we found that major vault protein (MVP) is expressed on the surface of HCC cells and further induced under stressful environments. MVP knockdown reduces cell proliferation and i...

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Publicado no:Sci Rep
Main Authors: Lee, Hyun Min, Joh, Jae Won, Seo, Se-Ri, Kim, Won-Tae, Kim, Min Kyu, Choi, Hong Seo, Kim, So Young, Jang, Young-Joo, Sinn, Dong Hyun, Choi, Gyu Seong, Kim, Jong Man, Kwon, Choon Hyuck David, Chang, Hee Jin, Kim, Dae Shick, Ryu, Chun Jeih
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643512/
https://ncbi.nlm.nih.gov/pubmed/29038587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13501-1
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