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Collision with duplex DNA renders Escherichia coli DNA polymerase III holoenzyme susceptible to DNA polymerase IV-mediated polymerase switching on the sliding clamp

Organisms possess multiple DNA polymerases (Pols) and use each for a different purpose. One of the five Pols in Escherichia coli, DNA polymerase IV (Pol IV), encoded by the dinB gene, is known to participate in lesion bypass at certain DNA adducts. To understand how cells choose Pols when the replic...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Le, Thanh Thi, Furukohri, Asako, Tatsumi-Akiyama, Masahiro, Maki, Hisaji
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643309/
https://ncbi.nlm.nih.gov/pubmed/29038530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13080-1
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