DNA polymerase IV mediates efficient and quick recovery of replication forks stalled at N(2)-dG adducts

Escherichia coli DNA polymerase IV (Pol IV, also known as DinB) is a Y-family DNA polymerase capable of catalyzing translesion DNA synthesis (TLS) on certain DNA lesions, and accumulating data suggest that Pol IV may play an important role in copying various kinds of spontaneous DNA damage including...

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Detalhes bibliográficos
Main Authors: Ikeda, Mio, Furukohri, Asako, Philippin, Gaelle, Loechler, Edward, Akiyama, Masahiro Tatsumi, Katayama, Tsutomu, Fuchs, Robert P., Maki, Hisaji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117773/
https://ncbi.nlm.nih.gov/pubmed/24957605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku547
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