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Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) gefitinib has demonstrated dramatic clinical efficacy in non-small cell lung cancer (NSCLC) patients. However, its therapeutic efficacy is ultimately limited by the development of acquired drug resistance. The aim of this study...

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Detaylı Bibliyografya
Yayımlandı:Toxicol Appl Pharmacol
Asıl Yazarlar: Liu, Zhongwei, Gao, Weimin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643250/
https://ncbi.nlm.nih.gov/pubmed/28942004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.09.017
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