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Chemotherapeutic Sensitization of Leptomycin B Resistant Lung Cancer Cells by Pretreatment with Doxorubicin

The development of novel targeted therapies has become an important research focus for lung cancer treatment. Our previous study has shown leptomycin B (LMB) significantly inhibited proliferation of lung cancer cells; however, p53 wild type lung cancer cells were resistant to LMB. Therefore, the obj...

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Detalhes bibliográficos
Main Authors: Lu, Chuanwen, Shao, Changxia, Cobos, Everardo, Singh, Kamaleshwar P., Gao, Weimin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296751/
https://ncbi.nlm.nih.gov/pubmed/22412944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032895
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