Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice

C1 esterase inhibitor (C1-INH) can inhibit multiple pathways (complement, contact-kinin, coagulation, and fibrinolysis) that are all implicated in the pathophysiology of asthma. We explored the effect of human plasma-derived C1-INH on allergic lung inflammation in a house dust mite (HDM) induced ast...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stroo, Ingrid, Yang, Jack, Anas, Adam A., de Boer, J. Daan, van Mierlo, Gerard, Roem, Dorina, Wouters, Diana, Engel, Ruchira, Roelofs, Joris J. T. H., van ‘t Veer, Cornelis, van der Poll, Tom, Zeerleder, Sacha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643136/
https://ncbi.nlm.nih.gov/pubmed/29036225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186652
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