A highly sensitive liquid chromatography electrospray ionization mass spectrometry method for quantification of TMA, TMAO and creatinine in mouse urine

Our method describes the quantification in mouse urine of trimethylamine (TMA), trimethylamine N-oxide (TMAO) and creatinine. The method combines derivatization of TMA, with ethyl bromoacetate, and LC chromatographic separation on an ACE C(18) column. The effluent was continuously electrosprayed int...

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Detaylı Bibliyografya
Yayımlandı:MethodsX
Asıl Yazarlar: Veeravalli, Sunil, Karu, Kersti, Phillips, Ian R., Shephard, Elizabeth A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2017
Konular:
Biochemistry, Genetics and Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643081/
https://ncbi.nlm.nih.gov/pubmed/29062719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mex.2017.09.004
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