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The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of α-dystroglycan
Dystroglycan (DG) is a highly glycosylated protein complex that links the cytoskeleton with the extracellular matrix, mediating fundamental physiological functions such as mechanical stability of tissues, matrix organization and cell polarity. A crucial role in the glycosylation of the DG α subunit...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643065/ https://ncbi.nlm.nih.gov/pubmed/29036200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186110 |
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