Genetic Engineering of Dystroglycan in Animal Models of Muscular Dystrophy

In skeletal muscle, dystroglycan (DG) is the central component of the dystrophin-glycoprotein complex (DGC), a multimeric protein complex that ensures a strong mechanical link between the extracellular matrix and the cytoskeleton. Several muscular dystrophies arise from mutations hitting most of the...

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Dades bibliogràfiques
Publicat a:Biomed Res Int
Autors principals: Sciandra, Francesca, Bigotti, Maria Giulia, Giardina, Bruno, Bozzi, Manuela, Brancaccio, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561298/
https://ncbi.nlm.nih.gov/pubmed/26380289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/635792
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