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Aligner optimization increases accuracy and decreases compute times in multi-species sequence data

As sequencing technologies have evolved, the tools to analyze these sequences have made similar advances. However, for multi-species samples, we observed important and adverse differences in alignment specificity and computation time for bwa- mem (Burrows–Wheeler aligner-maximum exact matches) relat...

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Detalhes bibliográficos
Publicado no:Microb Genom
Main Authors: Robinson, Kelly M., Hawkins, Aziah S., Santana-Cruz, Ivette, Adkins, Ricky S., Shetty, Amol C., Nagaraj, Sushma, Sadzewicz, Lisa, Tallon, Luke J., Rasko, David A., Fraser, Claire M., Mahurkar, Anup, Silva, Joana C., Dunning Hotopp, Julie C.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643015/
https://ncbi.nlm.nih.gov/pubmed/29114401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mgen.0.000122
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