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Using transmission electron microscopy and 3View® to determine collagen fibril size and three-dimensional organization

Collagen fibrils are the major tensile element in vertebrate tissues where they occur as ordered bundles in the extracellular matrix. Abnormal fibril assembly and organization results in scarring, fibrosis, poor wound healing and connective tissue diseases. Transmission electron microscopy (TEM) is...

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Bibliografske podrobnosti
izdano v:Nat Protoc
Main Authors: Starborg, Tobias, Kalson, Nicholas S., Lu, Yinhui, Mironov, Aleksandr, Cootes, Timothy F., Holmes, David F., Kadler, Karl E.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642902/
https://ncbi.nlm.nih.gov/pubmed/23807286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.086
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