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Single cell transcriptomics reveals receptor transformations during olfactory neurogenesis

The sense of smell allows chemicals to be perceived as diverse scents. We used single neuron RNA-Sequencing (RNA-Seq) to explore developmental mechanisms that shape this ability as nasal olfactory neurons mature in mice. Most mature neurons expressed only one of the roughly 1000 odorant receptor gen...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Hanchate, Naresh K., Kondoh, Kunio, Lu, Zhonghua, Kuang, Donghui, Ye, Xiaolan, Qiu, Xiaojie, Pachter, Lior, Trapnell, Cole, Buck, Linda B.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642900/
https://ncbi.nlm.nih.gov/pubmed/26541607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad2456
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