Connect-seq to superimpose molecular on anatomical neural circuit maps

The mouse brain contains about 75 million neurons interconnected in a vast array of neural circuits. The identities and functions of individual neuronal components of most circuits are undefined. Here we describe a method, termed “Connect-seq,” which combines retrograde viral tracing and single-cell...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Hanchate, Naresh K., Lee, Eun Jeong, Ellis, Andria, Kondoh, Kunio, Kuang, Donghui, Basom, Ryan, Trapnell, Cole, Buck, Linda B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049128/
https://ncbi.nlm.nih.gov/pubmed/32034095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912176117
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