YAP/TAZ-CDC42 signaling regulates vascular tip cell migration

Angiogenesis and vascular remodeling are essential for the establishment of vascular networks during organogenesis. Here we show that the Hippo signaling pathway effectors YAP and TAZ are required, in a gene dosage-dependent manner, for the proliferation and migration of vascular endothelial cells (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sakabe, Masahide, Fan, Jieqing, Odaka, Yoshinobu, Liu, Ning, Hassan, Aishlin, Duan, Xin, Stump, Paige, Byerly, Luke, Donaldson, Megan, Hao, Jiukuan, Fruttiger, Marcus, Lu, Qing Richard, Zheng, Yi, Lang, Richard A., Xin, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642684/
https://ncbi.nlm.nih.gov/pubmed/28973878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704030114
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