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The resistance mechanisms and treatment strategies for EGFR-mutant advanced non-small-cell lung cancer
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI) have been established as the standard therapy for EGFR-sensitizing mutant advanced non-small-cell lung cancer (NSCLC). However, patients ultimately develop resistance to these drugs. There are several mechanisms of both primary a...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642641/ https://ncbi.nlm.nih.gov/pubmed/29050366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20311 |
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