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Prox1 represses IL-2 gene expression by interacting with NFAT2

Interleukin-2 (IL-2) is critical for T lymphocyte activation and regulated by many transcriptional factors. Prospero-related homeobox 1 (Prox1) is a multifunctional transcription factor, which can work as either a transcriptional activator or repressor depending on the cellular and developmental env...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Shujie, Yu, Ning, Wang, Linfang, Liu, Yanfeng, Kong, Yuying, Liu, Jing, Xie, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642489/
https://ncbi.nlm.nih.gov/pubmed/29050214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17278
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