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Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)

Cancer stem cells (CSCs), which have the potential for self-renewal, differentiation and de-differentiation, undergo epigenetic, epithelial-mesenchymal, immunological and metabolic reprogramming to adapt to the tumor microenvironment and survive host defense or therapeutic insults. Intra-tumor heter...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Autor principal: Katoh, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642388/
https://ncbi.nlm.nih.gov/pubmed/29048660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.4129
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