Relation between NOD2 genotype and changes in innate signaling in Crohn’s disease on mRNA and miRNA levels

Crohn’s disease is associated with an altered innate immune response of pathogenic importance. This altered response can be associated to loss-of-function polymorphisms in the NOD2 (nucleotide-binding oligomerization domain-containing protein 2) gene, but also changes in transcriptional and post-tra...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Chen, Yun, Salem, Mohammad, Boyd, Mette, Bornholdt, Jette, Li, Yuan, Coskun, Mehmet, Seidelin, Jakob Benedict, Sandelin, Albin, Nielsen, Ole Haagen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642384/
https://ncbi.nlm.nih.gov/pubmed/29263823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-016-0001-4
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