Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease

OBJECTIVES: Autophagy-related 16-like 1 (ATG16L1) deficiency leads to impaired cellular autophagy and bacterial degradation as well as an altered cytokine production. The single-nucleotide polymorphism rs2241880 (T300A) is associated with an increased risk for Crohn's disease (CD). ATG16L1 poly...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Salem, Mohammad, Nielsen, Ole Haagen, Nys, Kris, Yazdanyar, Shiva, Seidelin, Jakob Benedict
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816087/
https://ncbi.nlm.nih.gov/pubmed/26673830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ctg.2015.47
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados