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Evaluation of recombinant factor VIII Fc (Eloctate) activity by thromboelastometry in a multicenter phase 3 clinical trial and correlation with bleeding phenotype

The aim of this study was to compare the hemostatic efficacy of recombinant factor VIII Fc (rFVIIIFc) (Eloctate) and Advate by ex-vivo rotation thromboelastometry (ROTEM) of whole blood and to explore potential ROTEM parameters that may be more predictive of a patient's bleeding tendency than p...

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Detalhes bibliográficos
Publicado no:Blood Coagul Fibrinolysis
Main Authors: Driessler, Frank, Miguelino, Maricel G., Pierce, Glenn F., Peters, Robert T., Sommer, Jurg M.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams And Wilkins 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642334/
https://ncbi.nlm.nih.gov/pubmed/28486277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000638
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