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Nano-Armoring of Enzymes: Rational Design of Polymer-Wrapped Enzymes

Proteins have the potential to replace synthetic small molecule drugs due to their specificity and selectivity in their activity. However, if administered in their native form, they can aggregate leading to immunogenicity or get cleared by renal and reticuloendothelial system which ultimately hamper...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Raghupathi, Kishore, Thayumanavan, S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642287/
https://ncbi.nlm.nih.gov/pubmed/28411646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.01.007
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