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Nano-Armoring of Enzymes: Rational Design of Polymer-Wrapped Enzymes

Proteins have the potential to replace synthetic small molecule drugs due to their specificity and selectivity in their activity. However, if administered in their native form, they can aggregate leading to immunogenicity or get cleared by renal and reticuloendothelial system which ultimately hamper...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Raghupathi, Kishore, Thayumanavan, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642287/
https://ncbi.nlm.nih.gov/pubmed/28411646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.01.007
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