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Distinct deposition of amyloid-β species in brains with Alzheimer’s disease pathology visualized with MALDI imaging mass spectrometry

Amyloid β (Aβ) deposition in the brain is an early and invariable feature of Alzheimer’s disease (AD). The Aβ peptides are composed of about 40 amino acids and are generated from amyloid precursor proteins (APP), by β- and γ-secretases. The distribution of individual Aβ peptides in the brains of age...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol Commun
Asıl Yazarlar: Kakuda, Nobuto, Miyasaka, Tomohiro, Iwasaki, Noriyuki, Nirasawa, Takashi, Wada-Kakuda, Satoko, Takahashi-Fujigasaki, Junko, Murayama, Shigeo, Ihara, Yasuo, Ikegawa, Masaya
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641992/
https://ncbi.nlm.nih.gov/pubmed/29037261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0477-x
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