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Casein kinase 1‐epsilon or 1‐delta required for Wnt‐mediated intestinal stem cell maintenance

The intestinal epithelium holds an immense regenerative capacity mobilized by intestinal stem cells (ISCs), much of it supported by Wnt pathway activation. Several unique regulatory mechanisms ensuring optimal levels of Wnt signaling have been recognized in ISCs. Here, we identify another Wnt signal...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Morgenstern, Yael, Das Adhikari, Upasana, Ayyash, Muneef, Elyada, Ela, Tóth, Beáta, Moor, Andreas, Itzkovitz, Shalev, Ben‐Neriah, Yinon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641904/
https://ncbi.nlm.nih.gov/pubmed/28963394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201696253
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