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Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

Mitochondrial production of superoxide and hydrogen peroxide is potentially important in cell signaling and disease. Eleven distinct mitochondrial sites that differ markedly in capacity are known to leak electrons to oxygen to produce O(2)(˙̄) and/or H(2)O(2). We discuss their contributions to O(2)(...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Wong, Hoi-Shan, Dighe, Pratiksha A., Mezera, Vojtech, Monternier, Pierre-Axel, Brand, Martin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641882/
https://ncbi.nlm.nih.gov/pubmed/28842493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.789271
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