Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight

OBJECTIVE: Intestinal metabolism might play a greater role in regulating whole body metabolism than previously believed. We aimed to enhance enterocyte metabolism in mice and investigate if it plays a role in diet-induced obesity (DIO) and its comorbidities. METHODS: Using the cre-loxP system, we ov...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Ramachandran, Deepti, Clara, Rosmarie, Fedele, Shahana, Hu, Junmin, Lackzo, Endre, Huang, Jing-Yi, Verdin, Eric, Langhans, Wolfgang, Mansouri, Abdelhak
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641632/
https://ncbi.nlm.nih.gov/pubmed/29031725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.07.009
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