Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss

OBJECTIVE: The mitochondrial uncoupling agent 2,4-dinitrophenol (DNP), historically used as a treatment for obesity, is known to cross the blood-brain-barrier, but its effects on central neural circuits controlling body weight are largely unknown. As hypothalamic melanocortin neuropeptide Y/agouti-r...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Mol Metab
Main Authors: Michael, Natalie Jane, Simonds, Stephanie Elise, van den Top, Marco, Cowley, Michael Alexander, Spanswick, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2017
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641603/
https://ncbi.nlm.nih.gov/pubmed/29031712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.07.002
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla