Загрузка...

Mitotic Activation of Protein-tyrosine Phosphatase α and Regulation of Its Src-mediated Transforming Activity by Its Sites of Protein Kinase C Phosphorylation

During mitosis, the catalytic activity of protein-tyrosine phosphatase (PTP) α is enhanced, and its inhibitory binding to Grb2, which specifically blocks Src dephosphorylation, is decreased. These effects act synergistically to activate Src in mitosis. We show here that these effects are abrogated b...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Zheng, Xin-Min, Resnick, Ross J., Shalloway, David
Формат: Artigo
Язык:Inglês
Опубликовано: 2002
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641391/
https://ncbi.nlm.nih.gov/pubmed/11923305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M201394200
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!