Yüklüyor......
Optimization of trans-Splicing for Huntington's Disease RNA Therapy
Huntington's disease (HD) is a devastating neurodegenerative disorder caused by a polyglutamine (polyQ) expansion in exon 1 of the Huntingtin (HTT) gene. We have previously demonstrated that spliceosome-mediated trans-splicing is a viable molecular strategy to specifically reduce and repair mut...
Kaydedildi:
| Yayımlandı: | Front Neurosci |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2017
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641306/ https://ncbi.nlm.nih.gov/pubmed/29066943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00544 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|