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Inhibiting PHD2 in bone marrow mesenchymal stem cells via lentiviral vector-mediated RNA interference facilitates the repair of periodontal tissue defects in SD rats

Hypoxia-inducible factors (HIFs) play an important role in angiogenesis, and they can activate the expression of several downstream angiogenic factors. HIF-1 is a major transcriptor of HIFs, composed of α and β subunits. Prolyl hydroxylase domain-containing protein 2 (PHD2) is the main catabolic enz...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Changxing, Li, Houxuan, Jiang, Jun, Zhang, Qian, Yan, Fuhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641161/
https://ncbi.nlm.nih.gov/pubmed/29069818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20243
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