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Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis

Animal-parasitic nematodes have thus far been largely refractory to genetic manipulation, and methods employed to effect RNA interference (RNAi) have been ineffective or inconsistent in most cases. We describe here a new approach for genetic manipulation of Nippostrongylus brasiliensis, a widely use...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hagen, Jana, Sarkies, Peter, Selkirk, Murray E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864396/
https://ncbi.nlm.nih.gov/pubmed/33497411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009286
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