Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling

Endoplasmic reticulum (ER) chaperone Prolyl 4-hydroxylase, beta polypeptide (P4HB) has previously been identified as a novel target for chemoresistance in glioblastoma multiforme (GBM). Yet its functional roles in glioma carcinogenesis remain elusive. In clinical analysis using human glioma specimen...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Sun, Stella, Kiang, Karrie M.Y., Ho, Amy S.W., Lee, Derek, Poon, Ming-Wai, Xu, Fei-Fan, Pu, Jenny K.S., Kan, Amanda N.C., Lee, Nikki P.Y., Liu, Xiao-Bing, Man, Kwan, Day, Philip J.R., Lui, Wai-Man, Fung, Ching-Fai, Leung, Gilberto K.K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641099/
https://ncbi.nlm.nih.gov/pubmed/29069756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18026
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