TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines

Microtubules are cellular targets for a variety of anticancer therapies because of their critical function in mitosis. Taxol belongs to a class of microtubule targeting agents that suppresses microtubule dynamics and interferes with the functioning of the mitotic spindle, thereby effectively blockin...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Tame, Mihoko A., Manjón, Anna G., Belokhvostova, Daria, Raaijmakers, Jonne A., Medema, René H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641069/
https://ncbi.nlm.nih.gov/pubmed/29069726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17740
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