Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer

Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown. Using a series of in vitro assays, we assessed the ability of albendazole to inhibit proliferation in 20 HNSCC cell lines acro...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Ghasemi, Farhad, Black, Morgan, Vizeacoumar, Frederick, Pinto, Nicole, Ruicci, Kara M., Le, Carson Cao Son Huu, Lowerison, Matthew R., Leong, Hon Sing, Yoo, John, Fung, Kevin, MacNeil, Danielle, Palma, David A., Winquist, Eric, Mymryk, Joe S., Boutros, Paul C., Datti, Alessandro, Barrett, John W., Nichols, Anthony C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641066/
https://ncbi.nlm.nih.gov/pubmed/29069723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17292
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