Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer

Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown. Using a series of in vitro assays, we assessed the ability of albendazole to inhibit proliferation in 20 HNSCC cell lines acro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ghasemi, Farhad, Black, Morgan, Vizeacoumar, Frederick, Pinto, Nicole, Ruicci, Kara M., Le, Carson Cao Son Huu, Lowerison, Matthew R., Leong, Hon Sing, Yoo, John, Fung, Kevin, MacNeil, Danielle, Palma, David A., Winquist, Eric, Mymryk, Joe S., Boutros, Paul C., Datti, Alessandro, Barrett, John W., Nichols, Anthony C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641066/
https://ncbi.nlm.nih.gov/pubmed/29069723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17292
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