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The pathophysiological role of mitochondrial oxidative stress in lung diseases
Mitochondria are critically involved in reactive oxygen species (ROS)-dependent lung diseases, such as lung fibrosis, asbestos, chronic airway diseases and lung cancer. Mitochondrial DNA (mtDNA) encodes mitochondrial proteins and is more sensitive to oxidants than nuclear DNA. Damage to mtDNA causes...
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| Publicado no: | J Transl Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640915/ https://ncbi.nlm.nih.gov/pubmed/29029603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1306-5 |
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