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The pathophysiological role of mitochondrial oxidative stress in lung diseases

Mitochondria are critically involved in reactive oxygen species (ROS)-dependent lung diseases, such as lung fibrosis, asbestos, chronic airway diseases and lung cancer. Mitochondrial DNA (mtDNA) encodes mitochondrial proteins and is more sensitive to oxidants than nuclear DNA. Damage to mtDNA causes...

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Detalles Bibliográficos
Publicado en:J Transl Med
Main Authors: Liu, Xiaojing, Chen, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640915/
https://ncbi.nlm.nih.gov/pubmed/29029603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1306-5
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