Reverse Genetics System Demonstrates that Rotavirus Nonstructural Protein NSP6 Is Not Essential for Viral Replication in Cell Culture

The use of overlapping open reading frames (ORFs) to synthesize more than one unique protein from a single mRNA has been described for several viruses. Segment 11 of the rotavirus genome encodes two nonstructural proteins, NSP5 and NSP6. The NSP6 ORF is present in the vast majority of rotavirus stra...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Komoto, Satoshi, Kanai, Yuta, Fukuda, Saori, Kugita, Masanori, Kawagishi, Takahiro, Ito, Naoto, Sugiyama, Makoto, Matsuura, Yoshiharu, Kobayashi, Takeshi, Taniguchi, Koki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640853/
https://ncbi.nlm.nih.gov/pubmed/28794037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00695-17
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