Pseudorabies Virus dUTPase UL50 Induces Lysosomal Degradation of Type I Interferon Receptor 1 and Antagonizes the Alpha Interferon Response

Alphaherpesviruses that establish persistent infections rely partly on their ability to evade host antiviral responses, notably the type I interferon (IFN) response. However, the mechanisms employed by alphaherpesviruses to avoid this response are not well understood. Pseudorabies virus (PRV) is an...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Zhang, Rui, Xu, Aotian, Qin, Chao, Zhang, Qiong, Chen, Shifan, Lang, Yue, Wang, Mengdong, Li, Chuang, Feng, Wenhai, Jiang, Zhengfan, Tang, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640830/
https://ncbi.nlm.nih.gov/pubmed/28794045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01148-17
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