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Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation
Two potent anti-MRSA tanshinone glycosides (1 and 2) were discovered by targeted microbial biotransformation, along with rapid identification via MS/MS networking. Serial reactions including dehydrogenation, demethylations, reduction, glycosylation and methylation have been observed after incubation...
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Yayımlandı: | Synth Syst Biotechnol |
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Asıl Yazarlar: | , , , , , , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
KeAi Publishing
2016
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640788/ https://ncbi.nlm.nih.gov/pubmed/29062942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2016.05.002 |
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