pH-Dependant Antifungal Activity of Valproic Acid against the Human Fungal Pathogen Candida albicans

Current antifungal drugs suffer from limitations including toxicity, the emergence of resistance and decreased efficacy at low pH that are typical of human vaginal surfaces. Here, we have shown that the antipsychotic drug valproic acid (VPA) exhibited a strong antifungal activity against both sensit...

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Vydáno v:Front Microbiol
Hlavní autoři: Chaillot, Julien, Tebbji, Faiza, García, Carlos, Wurtele, Hugo, Pelletier, René, Sellam, Adnane
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640775/
https://ncbi.nlm.nih.gov/pubmed/29062309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01956
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