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pH-Dependant Antifungal Activity of Valproic Acid against the Human Fungal Pathogen Candida albicans

Current antifungal drugs suffer from limitations including toxicity, the emergence of resistance and decreased efficacy at low pH that are typical of human vaginal surfaces. Here, we have shown that the antipsychotic drug valproic acid (VPA) exhibited a strong antifungal activity against both sensit...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Chaillot, Julien, Tebbji, Faiza, García, Carlos, Wurtele, Hugo, Pelletier, René, Sellam, Adnane
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640775/
https://ncbi.nlm.nih.gov/pubmed/29062309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01956
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