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Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

Establishment of cell polarity in the mammalian embryo is fundamental for the first cell fate decision that sets aside progenitor cells for both the new organism and the placenta. Yet the sequence of events and molecular mechanism that trigger this process remain unknown. Here, we show that de novo...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Zhu, Meng, Leung, Chuen Yan, Shahbazi, Marta N., Zernicka-Goetz, Magdalena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640629/
https://ncbi.nlm.nih.gov/pubmed/29030553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00977-8
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