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Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

Establishment of cell polarity in the mammalian embryo is fundamental for the first cell fate decision that sets aside progenitor cells for both the new organism and the placenta. Yet the sequence of events and molecular mechanism that trigger this process remain unknown. Here, we show that de novo...

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Publicado en:Nat Commun
Autores principales: Zhu, Meng, Leung, Chuen Yan, Shahbazi, Marta N., Zernicka-Goetz, Magdalena
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640629/
https://ncbi.nlm.nih.gov/pubmed/29030553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00977-8
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