Nasal DNA methylation differentiates corticosteroid treatment response in pediatric asthma: A pilot study

BACKGROUND: Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distinguish treatment response. MATERIALS AND METHODS: We...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Zhang, Xue, Biagini Myers, Jocelyn M., Yadagiri, Veda K., Ulm, Ashley, Chen, Xiaoting, Weirauch, Matthew T., Khurana Hershey, Gurjit K., Ji, Hong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640236/
https://ncbi.nlm.nih.gov/pubmed/29028809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186150
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