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Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism(1). The maternal genome inherited through the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the zygote. How these two epigenetically dis...

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Publicado en:Nature
Autores principales: Flyamer, Ilya M., Gassler, Johanna, Imakaev, Maxim, Brandão, Hugo B., Ulianov, Sergey V., Abdennur, Nezar, Razin, Sergey V., Mirny, Leonid A., Tachibana-Konwalski, Kikuë
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639698/
https://ncbi.nlm.nih.gov/pubmed/28355183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21711
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