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Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

BACKGROUND: Expression of group A and the A-like subset of group B Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is associated with severe malaria (SM). The diversity of var sequences combined with the challenges of distinct classification of patient pathologies has made studying the...

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Pubblicato in:BMC Med
Autori principali: Shabani, Estela, Hanisch, Benjamin, Opoka, Robert O., Lavstsen, Thomas, John, Chandy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639490/
https://ncbi.nlm.nih.gov/pubmed/29025399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0945-y
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