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Lewis Acid Enabled Copper-Catalyzed Asymmetric Synthesis of Chiral β-Substituted Amides
[Image: see text] Here we report that readily available silyl- and boron-based Lewis acids in combination with chiral copper catalysts are able to overcome the reactivity issues of unactivated enamides, known as the least reactive carboxylic acid derivatives, toward alkylation with organomagnesium r...
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| Yayımlandı: | J Am Chem Soc |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical
Society
2017
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5639465/ https://ncbi.nlm.nih.gov/pubmed/28960071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07344 |
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